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Indeed, COPD and lung cancer have many common biological mechanisms, including chronic inflammation, oxidative stress, matrix degradation, genetic susceptibility, lung barrier dysfunction, and epithelialmesenchymal transition (EMT) [4, 59, 61]

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Hatsukami Journal: Nature Reviews Cancer Journal ranking: Q1 Key takeaways: Smokeless tobacco and cigarette smoking contribute to cancer by exposing users to multiple carcinogens, and monitoring their exposure can help identify high-risk individuals for effective cancer prevention interventions

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